5-HT Receptor


5-HT receptors (5-hydroxytryptamine receptors,The serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

  • Procaine HCl EY2475

    Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.

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  • Trazodone HCl EY2412

    Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

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  • Pizotifen Malate EY2243

    Pizotifen is an antagonist of muscarinic receptors and a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity.

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  • GR 125487 sulfamate EI1216

    GR 125487 sulfamate是活性选择性 5-HT4 拮抗剂,体内具有活性。

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  • GR 127935 hydrochloride EI1217

    GR 127935 hydrochloride是活性选择性 5-HT1B/1D 拮抗剂。

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  • Procaine HCl EY2475

    Procaine is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.

    More
  • Trazodone HCl EY2412

    Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

    More
  • Pizotifen Malate EY2243

    Pizotifen is an antagonist of muscarinic receptors and a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity.

    More
  • GR 125487 sulfamate EI1216

    GR 125487 sulfamate是活性选择性 5-HT4 拮抗剂,体内具有活性。

    More
  • GR 127935 hydrochloride EI1217

    GR 127935 hydrochloride是活性选择性 5-HT1B/1D 拮抗剂。

    More
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